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Selected Peer-reviewed publications (Sorted by newest to oldest):

Boxer, E.E., Seng, C., Lukacsovich, D., Kim, J., Schwartz, S., Kennedy, M.J., Földy, C., and Aoto, J. (2021). Neurexin-3 defines synapse- and sex-dependent diversity of GABAergic inhibition in ventral subiculum. Cell Rep 37, 110098. Link

Cai, Y., Nielsen, B.E., Boxer, E.E., Aoto, J., and Ford, C.P. (2021). Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments. Neuron.

Restrepo, S., Schwartz, S.L., Kennedy, M.J., and Aoto, J. (2020). Measuring Transcellular Interactions through Protein Aggregation in a Heterologous Cell System. J Vis Exp.

Restrepo SLanger NJNelson KAAoto J. (2019) Modeling a Neurexin-3α human mutation in mouse neurons identifies a novel role in the regulation of transsynaptic signaling and neurotransmitter release at excitatory synapses. Journal of Neuroscience. 1261-19. doi: 10.1523/JNEUROSCI.1261-19.2019. PMID: 31578233

Dai J, Aoto J, Südhof TC. (2019) Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses. Neuron. 102(5):993-1008.e5. doi: 10.1016/j.neuron.2019.03.032. PMID: 31005376

Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ. (2019) A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron. 101(5):863-875.e6. doi: 10.1016/j.neuron.2019.01.002. PMID: 30704911


Purkey AM, Woolfrey KM, Crosby KC, Stich DG, Chick WS, Aoto J, Dell'Acqua ML. (2018) AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca2+-Permeable AMPA Receptors to Control LTP. Cell Rep. 25(4):974-987.e4. doi: 10.1016/j.celrep.2018.09.085. PMID: 30355502

Földy C, Darmanis S, Aoto J, Malenka RC, Quake SR, Südhof TC. (2016) Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons. Proc Natl Acad Sci U S A. 113(35):E5222-31. doi: 10.1073/pnas.1610155113. PMID: 27531958

Chanda S, Aoto J, Lee SJ, Wernig M, Südhof TC. (2016) Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking. Mol Psychiatry. 169-77. doi: 10.1038/mp.2015.20. PMID: 25778475


Pak CH*, Danko T*, Aoto J, Anderson GR, Maxeiner S, Wernig M, Südhof TC. (2015) Human Neuropsychiatric Disease Modeling using Conditonal Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell. 17(3):316-328. PMID: 26279266

* Co-first author

Anderson GR, Aoto J, Tabuchi K, Földy C, Covy J, Yee AX, Wu D, Chen L, Malenka RC, Südhof TC. (2015) Presynaptic b-Neurexins Control Excitatory Synaptic Strength and Regulate Synaptic Endocannabinoid Signaling. Cell. 162(3): 593-606. PMID: 26213384


Aoto J.#, Földy C, Ciurea-Ilcus SM, Tabuchi K, Südhof TC. (2015) Distinct Circuit-Dependent Essential Functions of Neurexin-3 in Regulating Presynaptic Release or Postsynaptic AMPA-Receptor Stability. Nature Neuroscience. 18(7): 997-1007. PMID: 26030848

            #Corresponding Author


Aoto J., Martinelli, DC, Tabuchi H, Malenka RC, Südhof TC. (2013) Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking. Cell, 154: 75-88. PMID: 23827676


Anderson GR, Galfin T, Xu W, Aoto J, Malenka RC, Südhof TC. (2012) Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development. PNAS, 109: 18120-18125. PMID: 23074245


Sarti F, Schroeder J, Aoto J, Chen L. (2012) Conditional RARa knockout mice reveal acute requirement for retinoic acid and RARa in homeostatic plasticity. Front Mol Neurosci. PMID: 22419906


Aoto J*, Nam, CI*, Poon MM*, Ting P, and Chen L. (2008) Synaptic scaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron, 60: 308-220. PMID: 18957222

            *Equal Contribution


Maghsoodi B, Poon MM, Nam CI, Aoto J, Ting P, and Chen L. (2008) Retinoic acid regulates RARa-mediated control of translation in dendritic RNA granules during homeostatic synaptic plasticity. Proc Natl Acad Sci U S A, 105: 16015-20. PMID: 18840692


Aoto J, Ting P, Maghsoodi B, Xu N, Henkemeyer M, and Chen L. (2007) Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation. J. Neurosci, 27: 7508-19. PMID: 17626212



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